Human TIGIT / VSTM3 Protein (Fc Tag) 10917-H02H from Sino Biological, Inc.

Product Specs
ItemHuman TIGIT / VSTM3 Protein (Fc Tag)
CompanySino Biological, Inc.
Price Supplier Page View Company Product Page
Catalog Number10917-H02H
Activity1.Loaded Recombinant Human TIGIT Protein, hFc Tag (Cat.No. 10917-H02H) on ProA Biosensor, can bind Recombinant Human CD155/PVR Protein, His Tag (Cat.No. 10109-H08H) with an affinity constant of 0.18 uM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Immobilized Recombinant Human TIGIT / VSTM3 Protein (Fc Tag) (Cat: 10917-H02H) at 2 µg/mL (100 µL/well) can bind Recombinant Human CD155 / PVR Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 10109-H41H-B), the EC50 is 5-15 ng/mL. (QC tested) 3.Immobilized Recombinant Human TIGIT / VSTM3 Protein (Fc Tag) (Cat: 10917-H02H) at 2 µg/mL (100 µL/well) can bind Recombinant Human Nectin-2 Protein (Fc & AVI Tag), Biotinylated (Cat: 10005-H41H-B), the EC50 is 230-690 ng/mL. (Routinely tested) 4.Immobilized Recombinant Human CD155 / PVR Protein (His Tag) (Cat: 10109-H08H) at 2.5 µg/mL (100 µL/well) can bind Recombinant Human TIGIT / VSTM3 Protein (Fc Tag) (Cat: 10917-H02H), the EC50 is 60-180 ng/mL. (Routinely tested)
Conjugate/TagC-human IgG1-Fc
FormatLyophilized from sterile PBS,pH7.4
Purity≥ 95% as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human TIGIT consists 353 amino acids and predicts a molecular mass of 39.2 kDa. As a result of glycosylation, human TIGIT migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameTIGIT
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameT cell immunoreceptor with Ig and ITIM domains
NCBI Gene AliasesVSIG9, VSTM3, WUCAM